Analysis of 5-Azacytidine Resistance Models Reveals a Set of Targetable Pathways

The mechanisms by which myelodysplastic syndrome (MDS) cells resist the effects of hypomethylating agents (HMA) are currently the subject of intensive research. A better understanding of mechanisms by which the MDS cell becomes to tolerate HMA and progresses to acute myeloid leukemia (AML) requires...

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Autors principals:	Lubomír Minařík, Kristýna Pimková, Juraj Kokavec, Adéla Schaffartziková, Fréderic Vellieux, Vojtěch Kulvait, Lenka Daumová, Nina Dusilková, Anna Jonášová, Karina Savvulidi Vargová, Petra Králová Viziová, Radislav Sedláček, Zuzana Zemanová, Tomáš Stopka
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-01-01
Col·lecció:	Cells
Matèries:	myelodysplastic syndrome Azacytidine resistance CDX mice PI3K/AKT signaling
Accés en línia:	https://www.mdpi.com/2073-4409/11/2/223
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