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EGR2 is an epigenomic regulator of phagocytosis and antifungal immunity in alveolar macrophages

Alveolar macrophages (AMs) act as gatekeepers of the lung’s immune responses, serving essential roles in recognizing and eliminating pathogens. The transcription factor (TF) early growth response 2 (EGR2) has been recently described as required for mature AMs in mice; however, its mechanisms of acti...

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Ngā kaituhi matua: Zsuzsanna Kolostyak, Dora Bojcsuk, Viktoria Baksa, Zsuzsa Mathene Szigeti, Krisztian Bene, Zsolt Czimmerer, Pal Boto, Lina Fadel, Szilard Poliska, Laszlo Halasz, Petros Tzerpos, Wilhelm K. Berger, Andres Villabona-Rueda, Zsofia Varga, Tunde Kovacs, Andreas Patsalos, Attila Pap, Gyorgy Vamosi, Peter Bai, Balazs Dezso, Matthew Spite, Franco R. D’Alessio, Istvan Szatmari, Laszlo Nagy
Hōputu: Artigo
Reo:Inglês
I whakaputaina: American Society for Clinical investigation 2024-09-01
Rangatū:JCI Insight
Ngā marau:
Infectious disease
Inflammation
Urunga tuihono:https://doi.org/10.1172/jci.insight.164009
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