Anti-inflammatory 25(OH)D3, a natural steroid hormone, may complement all-trans retinoic acid therapy for differentiation syndrome in acute promyelocytic leukemia

Abstract Differentiation syndrome (DS) is a serious complication with an unclear pathogenesis that arises following all-trans retinoic acid (ATRA) or arsenic trioxide induction therapy in acute promyelocytic leukemia (APL). DS symptoms include pyrexia, respiratory compromise, increased body mass, fl...

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Bibliografische Detailangaben

Hauptverfasser:	Károly Jambrovics, Wedean Al-Hadban, Anett Mázló-Türk, Istvan Szatmari, Boglárka Dobó, Gyula Reményi, Ádám Jóna, Gábor Koncz, Zoltán Balajthy
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2025-11-01
Schriftenreihe:	Cell Death and Disease
Online-Zugang:	https://doi.org/10.1038/s41419-025-08109-7
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