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Three doses of Sars-CoV-2 mRNA vaccine in older adults result in similar antibody responses but reduced cellular cytokine responses relative to younger adults

Objectives: Booster COVID-19 vaccinations are used to protect the elderly, a group vulnerable to severe disease. We compared humoral and cellular immunity in older versus younger adults up to eight months after administering a BNT16b2 booster vaccine dose. Next, we analyzed the plasma levels of solu...

Deskribapen osoa

Gorde:
Egile Nagusiak: Geir Bredholt, Marianne Sævik, Hanne Søyland, Thor Ueland, Fan Zhou, Rishi Pathirana, Anders Madsen, Juha Vahokoski, Sarah Lartey, Bente E. Halvorsen, Tuva B. Dahl, Mai-Chi Trieu, Kristin G.-I. Mohn, Karl Albert Brokstad, Pål Aukrust, Camilla Tøndel, Nina Langeland, Bjørn Blomberg, Rebecca Jane Cox
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2024-10-01
Saila:Vaccine: X
Gaiak:
SARS-CoV-2
mRNA vaccines
Aging
Neutralizing antibodies
Memory B cells
T-lymphocytes
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S2590136224001372
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