Three doses of Sars-CoV-2 mRNA vaccine in older adults result in similar antibody responses but reduced cellular cytokine responses relative to younger adults

Objectives: Booster COVID-19 vaccinations are used to protect the elderly, a group vulnerable to severe disease. We compared humoral and cellular immunity in older versus younger adults up to eight months after administering a BNT16b2 booster vaccine dose. Next, we analyzed the plasma levels of solu...

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Principais autores:	Geir Bredholt, Marianne Sævik, Hanne Søyland, Thor Ueland, Fan Zhou, Rishi Pathirana, Anders Madsen, Juha Vahokoski, Sarah Lartey, Bente E. Halvorsen, Tuva B. Dahl, Mai-Chi Trieu, Kristin G.-I. Mohn, Karl Albert Brokstad, Pål Aukrust, Camilla Tøndel, Nina Langeland, Bjørn Blomberg, Rebecca Jane Cox
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2024-10-01
叢編:	Vaccine: X
主題:	SARS-CoV-2 mRNA vaccines Aging Neutralizing antibodies Memory B cells T-lymphocytes
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2590136224001372
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