Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection.

Chronic infections are characterized by the inability to eliminate the persisting pathogen and often associated with functional impairment of virus-specific T-cell responses. Costimulation through Glucocorticoid-induced TNFR-related protein (GITR) can increase survival and function of effector T cel...

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Үндсэн зохиолчид:	Maria Fernanda Pascutti, Sulima Geerman, Edith Slot, Klaas P J M van Gisbergen, Louis Boon, Ramon Arens, Rene A W van Lier, Monika C Wolkers, Martijn A Nolte
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Public Library of Science (PLoS) 2015-03-01
Цуврал:	PLoS Pathogens
Онлайн хандалт:	http://europepmc.org/articles/PMC4349659?pdf=render
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!