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Bone Marrow Harbors a Unique Population of Dendritic Cells with the Potential to Boost Neutrophil Formation upon Exposure to Fungal Antigen

Apart from controlling hematopoiesis, the bone marrow (BM) also serves as a secondary lymphoid organ, as it can induce naïve T cell priming by resident dendritic cells (DC). When analyzing DCs in murine BM, we uncovered that they are localized around sinusoids, can (cross)-present antigens, become a...

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Principais autores: Marieke Goedhart, Edith Slot, Maria F. Pascutti, Sulima Geerman, Timo Rademakers, Benjamin Nota, Stephan Huveneers, Jaap D. van Buul, Katherine C. MacNamara, Carlijn Voermans, Martijn A. Nolte
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-12-01
Serier:Cells
Fag:
dendritic cells
bone marrow
hematopoiesis
granulopoiesis
fungal infection
zymosan
Online adgang:https://www.mdpi.com/2073-4409/11/1/55
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