Structural modification of a novel inhibitor for mycobacterium enoyl-acyl carrier protein reductase assisted by In silico structure-based drug screening

Background: Mycobacterium tuberculosis enoyl-acyl carrier protein reductase (mtInhA) is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls, and has been targeted in the development of anti-tuberculosis (TB) drugs. In our previous in silico structure-based dr...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Junichi Taira, Toshiki Nagano, Mitsuru Kitamura, Miho Yamaguchi, Hiroshi Sakamoto, Shunsuke Aoki
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Wolters Kluwer Medknow Publications 2020-01-01
Cyfres:	International Journal of Mycobacteriology
Pynciau:	enoyl-acyl carrier protein reductase gold program mycobacterium smegmatis mycobacterium tuberculosis structure-based drug screening
Mynediad Ar-lein:	http://www.ijmyco.org/article.asp?issn=2212-5531;year=2020;volume=9;issue=1;spage=12;epage=17;aulast=Taira
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!