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Fibroblast paracrine TNF-α signaling elevates integrin A5 expression in idiopathic pulmonary fibrosis (IPF)

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with a poor prognosis. Inflammatory cytokines play a significant role in IPF pathology. However, the fibroblast itself is also believed to be the primary effector in IPF. We hypothesized that the fibroblasts themse...

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Huvudupphov: Gali Epstein Shochet, Elizabetha Brook, Lilach Israeli-Shani, Evgeny Edelstein, David Shitrit
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2017-06-01
Serie:Respiratory Research
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Länkar:http://link.springer.com/article/10.1186/s12931-017-0606-x
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