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Nucleoredoxin Plays a Key Role in the Maintenance of Retinal Pigmented Epithelium Differentiation

Nucleoredoxin (Nrx) belongs to the Thioredoxin protein family and functions in redox-mediated signal transduction. It contains the dithiol active site motif Cys-Pro-Pro-Cys and interacts and regulates different proteins in distinct cellular pathways. Nrx was shown to be catalytically active in the i...

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Principais autores: Mariana I. Holubiec, Juan I. Romero, Claudia Urbainsky, Manuela Gellert, Pablo Galeano, Francisco Capani, Christopher Horst Lillig, Eva-Maria Hanschmann
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-06-01
coleção:Antioxidants
Assuntos:
nucleoredoxin
hypoxia-ischemia
reoxygenation
retina
RPE
differentiation
Acesso em linha:https://www.mdpi.com/2076-3921/11/6/1106
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