Epigenetic Modulation of TLR4 Expression by Sulforaphane Increases Anti-Inflammatory Capacity in Porcine Monocyte-Derived Dendritic Cells

Inflammation is regulated by epigenetic modifications, including DNA methylation and histone acetylation. Sulforaphane (SFN), a histone deacetylase (HDAC) inhibitor, is also a potent immunomodulatory agent, but its anti-inflammatory functions through epigenetic modifications remain unclear. Therefor...

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Hauptverfasser:	Xueqi Qu, Christiane Neuhoff, Mehmet Ulas Cinar, Maren Pröll, Ernst Tholen, Dawit Tesfaye, Michael Hölker, Karl Schellander, Muhammad Jasim Uddin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2021-05-01
Schriftenreihe:	Biology
Schlagworte:	epigenetic NF-κB pig anti-inflammatory response HDAC inhibitors
Online-Zugang:	https://www.mdpi.com/2079-7737/10/6/490
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