Pseudorabies virus induces natural killer cell depletion by GSDMD-mediated inflammation and pyroptosis to promote infection and lung injury

ABSTRACT Pseudorabies virus (PRV) infection induces a hyperinflammatory response to promote inflammatory injury in multiple tissues. However, the relative mechanism remains elusive. Herein, we first confirmed that PRV infection could trigger pyroptosis to cause lung injury, evidenced by the increase...

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Bibliografski detalji

Glavni autori:	Jing Chen, Guangming Zhao, Yi Yang, Yinhui Li, Yu Song, Daxia Li, Qian Du, Dewen Tong, Yong Huang
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology 2025-08-01
Serija:	Journal of Virology
Teme:	pseudorabies virus lung injury NK cell
Online pristup:	https://journals.asm.org/doi/10.1128/jvi.00415-25
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