Protective effects of the RAGE inhibitor azeliragon as a potential anti-Streptococcus pneumoniae therapeutic in sepsis models
The increasing antimicrobial resistance of Streptococcus pneumoniae (S. pneumoniae) presents a major therapeutic challenge and underscores the need for agents with novel mechanisms of action. Azeliragon is a small-molecule inhibitor of the receptor for advanced glycation end products (RAGE), but its...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2026-04-01
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| Collection: | Frontiers in Medicine |
| Sujets: | |
| Accès en ligne: | https://www.frontiersin.org/articles/10.3389/fmed.2026.1793580/full |
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