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Protective effects of the RAGE inhibitor azeliragon as a potential anti-Streptococcus pneumoniae therapeutic in sepsis models

The increasing antimicrobial resistance of Streptococcus pneumoniae (S. pneumoniae) presents a major therapeutic challenge and underscores the need for agents with novel mechanisms of action. Azeliragon is a small-molecule inhibitor of the receptor for advanced glycation end products (RAGE), but its...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lei Zhang, Hao Lu, Hao Zhou
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2026-04-01
Saila:Frontiers in Medicine
Gaiak:
Sarrera elektronikoa:https://www.frontiersin.org/articles/10.3389/fmed.2026.1793580/full
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