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Leptin signaling and the intervertebral disc: Sex dependent effects of leptin receptor deficiency and Western diet on the spine in a type 2 diabetes mouse model.

Type 2 diabetes and obesity are associated with back pain in juveniles and adults and are implicated in intervertebral disc (IVD) degeneration. Hypercaloric Western diets are associated with both obesity and type 2 diabetes. The objective of this study was to determine if obesity and type 2 diabetes...

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Bibliografski detalji
Glavni autori: Devorah M Natelson, Alon Lai, Divya Krishnamoorthy, Robert C Hoy, James C Iatridis, Svenja Illien-Jünger
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2020-01-01
Serija:PLoS ONE
Online pristup:https://doi.org/10.1371/journal.pone.0227527
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