Targeting advanced glycation end products: potential therapeutic approaches for mitigating diabetic intervertebral disc degeneration?

Diabetes mellitus is strongly associated with accelerated intervertebral disc degeneration, a condition that significantly contributes to lower back pain and reduced quality of life. Emerging evidence indicates that advanced glycation end products (AGEs) are key mediators in the pathophysiology of d...

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Hlavní autoři:	Luyang Wang, Qipeng Shao, Haiyang Wu, Cheng Li
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-07-01
Edice:	Frontiers in Endocrinology
Témata:	advanced glycation end products diabetes mellitus intervertebral disc degeneration therapeutic target AGEs
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1618984/full
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