Interaction of microtubule depolymerizing agent indanocine with different human αβ tubulin isotypes.
Tubulin isotypes are known to regulate the stability and dynamics of microtubules, and are also involved in the development of resistance against microtubule-targeted cancer drugs. Indanocine, a potent microtubule depolymerizing agent, is highly active against multidrug-resistant (MDR) cancer cells...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2018-01-01
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| Serier: | PLoS ONE |
| Online adgang: | http://europepmc.org/articles/PMC5870988?pdf=render |
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