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Degradation of voltage-gated calcium channels: mechanisms and applications in neurological and cardiovascular diseases

Abstract The degradation of voltage-gated calcium channels (VGCC), which are key determinants of neuronal excitability and muscle contraction, is crucial for regulating calcium homeostasis and can be targeted for analgesic drug discovery. Molecularly, both the ubiquitin-proteasomal system and lysoso...

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書誌詳細
主要な著者: Lihong Liu, Yanruo Zhou, Ping Liao, Tuck Wah Soong, Zhenyu Hu
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2025-07-01
シリーズ:Cell Communication and Signaling
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オンライン・アクセス:https://doi.org/10.1186/s12964-025-02347-0
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