Degradation of voltage-gated calcium channels: mechanisms and applications in neurological and cardiovascular diseases
Abstract The degradation of voltage-gated calcium channels (VGCC), which are key determinants of neuronal excitability and muscle contraction, is crucial for regulating calcium homeostasis and can be targeted for analgesic drug discovery. Molecularly, both the ubiquitin-proteasomal system and lysoso...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2025-07-01
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| Serier: | Cell Communication and Signaling |
| Fag: | |
| Online adgang: | https://doi.org/10.1186/s12964-025-02347-0 |
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