Clinical Assessment of Breast Cancer Resistance Protein (BCRP)-Mediated Drug–Drug Interactions of Sepiapterin with Curcumin and Rosuvastatin in Healthy Volunteers

Abstract Background and Objective Sepiapterin, also known as PTC923 and CNSA-001, is a synthetic form of endogenous sepiapterin being developed as a novel oral treatment for phenylketonuria. Sepiapterin is a natural precursor of tetrahydrobiopterin (BH4) and, when orally administered, is converted t...

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Hauptverfasser:	Lan Gao, Diksha Kaushik, Kimberly Ingalls, Sarah Milner, Neil Smith, Ronald Kong
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Adis, Springer Healthcare 2024-09-01
Schriftenreihe:	Drugs in R&D
Online-Zugang:	https://doi.org/10.1007/s40268-024-00488-0
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