Masking the transmembrane region of the amyloid β precursor protein as a safe means to lower amyloid β production

Abstract Introduction Reducing brain levels of both soluble and insoluble forms of amyloid beta (Aβ) remains the primary goal of most therapies that target Alzheimer's disease (AD). However, no treatment has so far resulted in patient benefit, and clinical trials of the most promising drug candidate...

Descripción completa

Detalles Bibliográficos

Autores principales:	Ayesha Khan, Richard Killick, Daniel Wirth, Dominique Hoogland, Kalina Hristova, Jakob P. Ulmschneider, Christopher R. King, Martin B. Ulmschneider
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2023-10-01
Colección:	Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Materias:	Alzheimer's precursor protein amyloid beta molecular dynamics protein folding transmembrane domain
Acceso en línea:	https://doi.org/10.1002/trc2.12428
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!