Mutagenesis of the Varicella-Zoster Virus Genome Demonstrates That VLT and VLT-ORF63 Proteins Are Dispensable for Lytic Infection

Primary varicella-zoster virus (VZV) infection leads to varicella and the establishment of lifelong latency in sensory ganglion neurons. Reactivation of latent VZV causes herpes zoster, which is frequently associated with chronic pain. Latent viral gene expression is restricted to the VZV latency-as...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Shirley E. Braspenning, Robert Jan Lebbink, Daniel P. Depledge, Claudia M. E. Schapendonk, Laura A. Anderson, Georges M. G. M. Verjans, Tomohiko Sadaoka, Werner J. D. Ouwendijk
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2021-11-01
Цуврал:	Viruses
Нөхцлүүд:	varicella-zoster virus VLT VLT-ORF63 CRISPR/Cas9 BAC mutagenesis
Онлайн хандалт:	https://www.mdpi.com/1999-4915/13/11/2289
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!