Sex-specific regulation of the cardiac transcriptome by the protein phosphatase 2A regulatory subunit B55α

Abstract Protein phosphatase 2A (PP2A) regulatory subunit B55α has been implicated in the transcriptional regulation of cardiac growth and fibrosis by suppressing HDAC5/MEF2 signalling in cardiomyocytes. We created and characterised two mouse models with global or cardiomyocyte-specific disruption o...

Descripció completa

Dades bibliogràfiques

Autors principals:	Nicola M. Sergienko, Adam J. Trewin, Helen Kiriazis, Antonia J. A. Raaijmakers, Daniel G. Donner, Victoria C. Garside, Kelly A. Smith, James R. Bell, Kimberley M. Mellor, Lea M. D. Delbridge, Julie R. McMullen, Kate L. Weeks
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-11-01
Col·lecció:	npj Metabolic Health and Disease
Accés en línia:	https://doi.org/10.1038/s44324-024-00033-2
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!