Phosphatidylinositol4-phosphate 5-kinase prevents the decrease in the HERG potassium current induced by Gq protein-coupled receptor stimulation

The human ether-a-go-go-related gene (HERG) potassium current (IHERG) has been shown to decrease in amplitude following stimulation with Gq protein-coupled receptors (GqRs), such as α1-adrenergic and M1-muscarinic receptors (α1R and M1R, respectively), at least partly via the reduction of membrane p...

Descripció completa

Dades bibliogràfiques

Autors principals:	Taeko Kubo, Wei-Guang Ding, Futoshi Toyoda, Yusuke Fujii, Mariko Omatsu-Kanbe, Hiroshi Matsuura
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2015-01-01
Col·lecció:	Journal of Pharmacological Sciences
Matèries:	PI(4)P5-K HERG channel PI(4,5)P2 Gq protein-coupled receptors Arrhythmia
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S1347861314000218
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!