Long-term calcium imaging reveals functional development in hiPSC-derived cultures comparable to human but not rat primary cultures

Summary: Models for human brain-oriented research are often established on primary cultures from rodents, which fails to recapitulate cellular specificity and molecular cues of the human brain. Here we investigated whether neuronal cultures derived from human induced pluripotent stem cells (hiPSCs)...

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Bibliografiske detaljer

Principais autores:	Estefanía Estévez-Priego, Martina Moreno-Fina, Emanuela Monni, Zaal Kokaia, Jordi Soriano, Daniel Tornero
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2023-01-01
Serier:	Stem Cell Reports
Fag:	neural stem cells neuronal networks human cellular models calcium imaging functional connectivity human iPSCs
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2213671122005471
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