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Optimized quantification of intra-host viral diversity in SARS-CoV-2 and influenza virus sequence data

ABSTRACT High error rates of viral RNA-dependent RNA polymerases lead to diverse intra-host viral populations during infection. Errors made during replication that are not strongly deleterious to the virus can lead to the generation of minority variants. However, accurate detection of minority varia...

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Bibliografiset tiedot
Päätekijät: A. E. Roder, K. E. E. Johnson, M. Knoll, M. Khalfan, B. Wang, S. Schultz-Cherry, S. Banakis, A. Kreitman, C. Mederos, J.-H. Youn, R. Mercado, W. Wang, M. Chung, D. Ruchnewitz, M. I. Samanovic, M. J. Mulligan, M. Lässig, M. Luksza, S. Das, D. Gresham, E. Ghedin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2023-08-01
Sarja:mBio
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Linkit:https://journals.asm.org/doi/10.1128/mbio.01046-23
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