Liraglutide modulates GABAergic signaling in rat hippocampal CA3 pyramidal neurons predominantly by presynaptic mechanism

Abstract Background γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the brain where it regulates activity of neuronal networks. The receptor for glucagon-like peptide-1 (GLP-1) is expressed in the hippocampus, which is the center for memory and learning. In this study we examin...

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Ngā kaituhi matua:	Omar Babateen, Sergiy V. Korol, Zhe Jin, Amol K. Bhandage, Aikeremu Ahemaiti, Bryndis Birnir
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2017-12-01
Rangatū:	BMC Pharmacology and Toxicology
Ngā marau:	GABA GLP-1 receptor Patch-clamp Inhibitory postsynaptic and tonic currents Hippocampus Electrophysiology
Urunga tuihono:	http://link.springer.com/article/10.1186/s40360-017-0191-0
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!