Liraglutide modulates GABAergic signaling in rat hippocampal CA3 pyramidal neurons predominantly by presynaptic mechanism

Abstract Background γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the brain where it regulates activity of neuronal networks. The receptor for glucagon-like peptide-1 (GLP-1) is expressed in the hippocampus, which is the center for memory and learning. In this study we examin...

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Principais autores:	Omar Babateen, Sergiy V. Korol, Zhe Jin, Amol K. Bhandage, Aikeremu Ahemaiti, Bryndis Birnir
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2017-12-01
Series:	BMC Pharmacology and Toxicology
Assuntos:	GABA GLP-1 receptor Patch-clamp Inhibitory postsynaptic and tonic currents Hippocampus Electrophysiology
Acceso en liña:	http://link.springer.com/article/10.1186/s40360-017-0191-0
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