Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation
The calcium release-activated calcium channel Orai regulates Ca2+ entry into non-excitable cells and is required for proper immune function. While the channel typically opens following Ca2+ release from the endoplasmic reticulum, certain pathologic mutations render the channel constitutively open. P...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications Ltd
2020-11-01
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| Serija: | eLife |
| Teme: | |
| Online dostop: | https://elifesciences.org/articles/62772 |
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