The tight junction protein claudin 6 is a potential target for patient-individualized treatment in esophageal and gastric adenocarcinoma and is associated with poor prognosis

Abstract Background The prognosis of esophageal adenocarcinoma (EAC) and gastric adenocarcinoma (GAC) remains poor, and new therapeutic approaches are urgently needed. Claudin 6 (CLDN6) is an oncofetal antigen that is largely absent in healthy tissues and upregulated in several cancers, making it a...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Adrian Georg Simon, Su Ir Lyu, Mark Laible, Stefan Wöll, Özlem Türeci, Uğur Şahin, Hakan Alakus, Luca Fahrig, Thomas Zander, Reinhard Buettner, Christiane Josephine Bruns, Wolfgang Schroeder, Florian Gebauer, Alexander Quaas
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2023-08-01
Цуврал:	Journal of Translational Medicine
Нөхцлүүд:	Adenocarcinoma CAR T-cell therapy Immunotherapy Claudin CLDN6 Tight junctions
Онлайн хандалт:	https://doi.org/10.1186/s12967-023-04433-8
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!