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Thyroid hormone response element half-site organization and its effect on thyroid hormone mediated transcription.

Thyroid hormone (TH) exerts its effects by binding to the thyroid hormone receptor (TR), which binds to TH response elements (TREs) to regulate target gene expression. We investigated the relative ability of liganded homodimers TR and retinoid X receptor (RXR), and the heterodimer TR/RXR, to regulat...

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I tiakina i:
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Ngā kaituhi matua: Martin A Paquette, Ella Atlas, Mike G Wade, Carole L Yauk
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2014-01-01
Rangatū:PLoS ONE
Urunga tuihono:http://europepmc.org/articles/PMC4074170?pdf=render
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