The low complexity linker of DNAJB6b is key to its anti-amyloid function
Neurodegenerative disorders, such as Alzheimer’s and Parkinson’s diseases, are associated with the formation of amyloid fibrils. The DNAJB6b (JB6) chaperone greatly inhibits the disease-related self-assembly of amyloid peptides in an ATP-independent manner. The molecular basis of this process is, ho...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cambridge University Press
2025-01-01
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| Collection: | QRB Discovery |
| Sujets: | |
| Accès en ligne: | https://www.cambridge.org/core/product/identifier/S2633289225100161/type/journal_article |
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