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Probing Combined Experimental and Computational Profiling to Identify <i>N</i>-(benzo[d]thiazol-2-yl) Carboxamide Derivatives: A Path to Potent α-Amylase and α-Glucosidase Inhibitors for Treating Diabetes Mellitus

A novel series of benzothiazole scaffolds were presented to test their in vitro α-amylase and α-glucosidase activities for combating diabetes mellitus, which is one of the most rapidly growing diseases. The tested compounds were elucidated structurally by various spectroscopic techniques like <sup>1...

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Principais autores: Fakhria A. Al-Joufi, Mariam Mojally, Maher S. Alwethaynani, Nawal Al-Hoshani, Ghulam Nabi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-02-01
Serier:Molecules
Fag:
benzothiazole
SAR
α-amylase
α-glucosidase
DFT
molecular docking
Online adgang:https://www.mdpi.com/1420-3049/31/4/751
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