Collagen-specific molecular chaperone Hsp47 in inguinal white adipose tissue promotes high-fat diet-induced inflammatory gene expression in male mice
Abstract A chronic high-fat diet (HFD) leads to obesity through a process involving adipocyte hypertrophy, hyperplasia, induction of pro-inflammatory gene expression, and ultimately fibrosis that impairs systemic health. Adipocytes are surrounded by an extracellular matrix (ECM) containing collagen....
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2026-03-01
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| Series: | Scientific Reports |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1038/s41598-026-45003-4 |
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