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HSP47: A Therapeutic Target in Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by a progressive decline in lung function and poor prognosis. The deposition of the extracellular matrix (ECM) by myofibroblasts contributes to the stiffening of lung tissue and impaired oxygen exchange in IPF. Type I collag...

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Principais autores: Noriho Sakamoto, Daisuke Okuno, Takatomo Tokito, Hirokazu Yura, Takashi Kido, Hiroshi Ishimoto, Yoshimasa Tanaka, Hiroshi Mukae
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-08-01
Serier:Biomedicines
Fag:
heat shock protein 47
pulmonary fibrosis
anti-fibrotic agent
collagen
chaperon
<i>SERPINH1</i>
Online adgang:https://www.mdpi.com/2227-9059/11/9/2387
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