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Identification of novel drug targets for liver cirrhosis and its potential side-effects by human plasma proteome

Abstract Liver cirrhosis, a common liver disease, currently lacks specific targeted therapies. This study investigates the potential therapeutic effects of serum circulating proteins on cirrhosis from a genetic perspective, and identified six associated plasma proteins (SERPINA1, PSG5, NCAN, APOE, A...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Qing-Ao Xiao, Wen-Jiang Zhao, Jing Yu, Lei Qin, Xiao-Lin Zhang, Jin Yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2024-11-01
Schriftenreihe:Scientific Reports
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Online-Zugang:https://doi.org/10.1038/s41598-024-80483-2
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