Novel therapeutic targets for primary open-angle glaucoma identified through multicenter proteome-wide mendelian randomization

BackgroundThis study aimed to identify novel therapeutic targets for primary open-angle glaucoma (POAG).MethodsThe summary-data-based Mendelian randomization (SMR) method was used to evaluate the genetic association between plasma proteins and POAG. Two sets of plasma protein quantitative trait loci...

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Autores principales:	Weichen Yuan, Jun Li, Shang Gao, Wei Sun, Fangkun Zhao
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2024-08-01
Colección:	Frontiers in Pharmacology
Materias:	Mendelian randomization drug targets therapy primary open angle glaucoma (POAG) plasma proteins
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1428472/full
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