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GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and KV7 Channel Blockers in Rat Small Mesenteric Arteries

Donors of H2S may be beneficial in treating cardiovascular diseases where the plasma levels of H2S are decreased. Therefore, we investigated the mechanisms involved in relaxation of small arteries induced by GYY4137 [(4-methoxyphenyl)-morpholin-4-yl-sulfanylidene-sulfido-λ5-phosphane;morpholin-4-ium...

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Auteurs principaux: Silvijus Abramavicius, Asbjørn G. Petersen, Nirthika S. Renaltan, Judit Prat-Duran, Roberta Torregrossa, Edgaras Stankevicius, Matthew Whiteman, Ulf Simonsen
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021-03-01
Collection:Frontiers in Pharmacology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fphar.2021.613989/full
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