GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and KV7 Channel Blockers in Rat Small Mesenteric Arteries

Donors of H2S may be beneficial in treating cardiovascular diseases where the plasma levels of H2S are decreased. Therefore, we investigated the mechanisms involved in relaxation of small arteries induced by GYY4137 [(4-methoxyphenyl)-morpholin-4-yl-sulfanylidene-sulfido-λ5-phosphane;morpholin-4-ium...

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Hlavní autoři:	Silvijus Abramavicius, Asbjørn G. Petersen, Nirthika S. Renaltan, Judit Prat-Duran, Roberta Torregrossa, Edgaras Stankevicius, Matthew Whiteman, Ulf Simonsen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-03-01
Edice:	Frontiers in Pharmacology
Témata:	GYY4137 sodium sulfide hydrogen sulfide potassium channels small mesenteric arteries
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2021.613989/full
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