Disruption of cerebral cholesterol homeostasis by PS-NPs: astrocytic endoplasmic reticulum stress

Abstract Cholesterol plays a crucial role in regulating synaptic membrane fluidity and ion channels. Due to the blood-brain barrier, cholesterol in the brain is primarily self-synthesized by astrocytes. However, limited research has been conducted on the effects of polystyrene nanoplastic (PS-NPs) o...

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Detalhes bibliográficos

Principais autores:	Lei Tian, Yizhe Wei, Jianping Ma, Yiming Zhao, Yanan Mi, Leili Zhang, Bingyan Wang, Jiang Chen, Kang Li, Yue Shi, Wenqing Lai, Huanliang Liu, Bencheng Lin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
coleção:	Journal of Nanobiotechnology
Assuntos:	Nanoplastics Astrocytes Cholesterol Endoplasmic reticulum stress
Acesso em linha:	https://doi.org/10.1186/s12951-025-03949-z
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