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Disruption of cerebral cholesterol homeostasis by PS-NPs: astrocytic endoplasmic reticulum stress

Abstract Cholesterol plays a crucial role in regulating synaptic membrane fluidity and ion channels. Due to the blood-brain barrier, cholesterol in the brain is primarily self-synthesized by astrocytes. However, limited research has been conducted on the effects of polystyrene nanoplastic (PS-NPs) o...

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Hlavní autoři: Lei Tian, Yizhe Wei, Jianping Ma, Yiming Zhao, Yanan Mi, Leili Zhang, Bingyan Wang, Jiang Chen, Kang Li, Yue Shi, Wenqing Lai, Huanliang Liu, Bencheng Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-12-01
Edice:Journal of Nanobiotechnology
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On-line přístup:https://doi.org/10.1186/s12951-025-03949-z
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