Identification of RPGRIP1L as an instability-maintaining gene to drive tumor growth and PD-L1 expression via Hedgehog signaling in breast cancer
Abstract Genomic instability is a hallmark of nearly all human cancers, yet the genetic regulators that govern this instability, their functional roles, and their therapeutic potential remain incompletely understood in breast cancer. In this study, we conducted a comprehensive analysis of the expres...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2025-12-01
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| Col·lecció: | BMC Cancer |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1186/s12885-025-15500-2 |
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