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CIRBP Stabilizes <i>Slc7a11</i> mRNA to Sustain the SLC7A11/GPX4 Antioxidant Axis and Limit Ferroptosis in Doxorubicin-Induced Cardiotoxicity

Doxorubicin-induced cardiotoxicity (DIC) significantly constrains the clinical efficacy of anthracycline chemotherapy, primarily through the induction of ferroptosis, an iron-dependent, regulated cell death driven by oxidative stress and lipid peroxidation. However, the upstream regulators of ferrop...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yixin Xie, Yongnan Li, Yafei Xie, Jianshu Chen, Hong Ding, Xiaowei Zhang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2025-07-01
Rangatū:Antioxidants
Ngā marau:
Urunga tuihono:https://www.mdpi.com/2076-3921/14/8/930
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