Predictors of early response to GnRH and gonadotropin therapy in pediatric patients with suspected dual congenital hypogonadotropic hypogonadism: a retrospective single-center study

ObjectiveSome patients with congenital hypogonadotropic hypogonadism (CHH) and suspected partial testicular impairment may show variable clinical responses to GnRH and gonadotropin therapy, but predictors of early treatment responsiveness remain unclear. This study aimed to investigate the predictiv...

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Autori principali:	Qin Zhang, Yi Wang, Bingyan Cao, Xinmeng Wang, Zheng Yuan, Xinyu Dou, Chunxiu Gong
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-05-01
Serie:	Frontiers in Endocrinology
Soggetti:	biomarker congenital hypogonadotropic hypogonadism GnRH and gonadotropin therapy pediatric patients suspected dual defect
Accesso online:	https://www.frontiersin.org/articles/10.3389/fendo.2026.1844974/full
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