Structural and functional analyses of SARS-CoV-2 Nsp3 and its specific interactions with the 5’ UTR of the viral genome
ABSTRACT Non-structural protein 3 (Nsp3) is the largest open reading frame encoded in the SARS-CoV-2 genome, essential for the formation of double-membrane vesicles (DMV) wherein viral RNA replication occurs. We conducted an extensive structure-function analysis of Nsp3 and determined the crystal st...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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American Society for Microbiology
2025-08-01
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| Serie: | Microbiology Spectrum |
| Soggetti: | |
| Accesso online: | https://journals.asm.org/doi/10.1128/spectrum.02871-24 |
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