Identification of Post-Transcriptional Modulators of Breast Cancer Transcription Factor Activity Using MINDy.

We have recently identified transcription factors (TFs) that are key drivers of breast cancer risk. To better understand the pathways or sub-networks in which these TFs mediate their function we sought to identify upstream modulators of their activity. We applied the MINDy (Modulator Inference by Ne...

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Hauptverfasser: Thomas M Campbell, Mauro A A Castro, Bruce A J Ponder, Kerstin B Meyer
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2016-01-01
Schriftenreihe:PLoS ONE
Online Zugang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0168770&type=printable
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