Intranasal administration of poly(I:C) and LPS in BALB/c mice induces airway hyperresponsiveness and inflammation via different pathways.

BACKGROUND: Bacterial and viral infections are known to promote airway hyperresponsiveness (AHR) in asthmatic patients. The mechanism behind this reaction is poorly understood, but pattern recognizing Toll-like receptors (TLRs) have recently been suggested to play a role. MATERIALS AND METHODS: To e...

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Hlavní autoři:	Magnus Starkhammar, Susanna Kumlien Georén, Linda Swedin, Sven-Erik Dahlén, Mikael Adner, Lars Olaf Cardell
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2012-01-01
Edice:	PLoS ONE
On-line přístup:	http://europepmc.org/articles/PMC3280225?pdf=render
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