Protrudin acts at ER-endosome contacts to promote KIF5-mediated endosomal tubule fission

Defective endosomal sorting and trafficking are increasingly recognised as key drivers of neurodegeneration, including hereditary spastic paraplegia (HSP) and other motor neuron disorders. Early endosomal tubule fission (ETF) is essential for sorting cargoes for recycling and retrograde transport, y...

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Principais autores:	Julia Kleniuk, Aishwarya G. Nadadhur, Catherine Rodger, Emily Wolfenden, Isabelle A. Hall, Samuel R. Cheers, Eliska Zlamalova, Evan Reid
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2026-01-01
Serija:	Neurobiology of Disease
Teme:	Endosomal sorting Endosomal tubule fission Endoplasmic reticulum Organelle contacts
Online dostop:	http://www.sciencedirect.com/science/article/pii/S0969996125004486
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