3D hanging spheroid plate for high-throughput CAR T cell cytotoxicity assay
Abstract Background Most high-throughput screening (HTS) systems studying the cytotoxic effect of chimeric antigen receptor (CAR) T cells on tumor cells rely on two-dimensional cell culture that does not recapitulate the tumor microenvironment (TME). Tumor spheroids, however, can recapitulate the TM...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2022-01-01
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| Schriftenreihe: | Journal of Nanobiotechnology |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1186/s12951-021-01213-8 |
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