Decoding TNF receptor superfamily control of CD4+Foxp3+ Regulatory T cell-mediated tolerance: implications for the treatment of graft‑versus‑host disease

Abstract Allogeneic transplantation is a cornerstone treatment for hematologic malignancies and organ failure, yet its success is limited by graft-versus-host disease (GvHD) and allograft rejection. Conventional broad-spectrum immunosuppression compromises protective graft-versus-leukemia (GvL) effe...

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Principais autores:	Chon-Kit Chou, Xinyang Wang, Ruiqi Yu, Hang Xu, Yibo Chen, Yang Yang, Zhonghao Chen, Chuangen Li, Tianzhen He, Xin Chen
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2026-06-01
סדרה:	Cell Communication and Signaling
נושאים:	Tregs TNF Receptor Superfamily TNFRSF GvHD Transplantation Treg Expansion
גישה מקוונת:	https://doi.org/10.1186/s12964-026-02990-1
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